Phosphoribosylformylglycinamidine Synthase (PFAS) (N-Term) Peptide
Quick Overview for Phosphoribosylformylglycinamidine Synthase (PFAS) (N-Term) Peptide (ABIN8108221)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- PFAS Peptide - N-terminal region
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Sequence
- LRPEDPTRPS RFQQQQGLRH VVFTAETHNF PTGVCPFSGA TTGTGGRIRD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-PUR4 Antibody (ARP46181_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PFAS (Phosphoribosylformylglycinamidine Synthase (PFAS))
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Background
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Background Information: Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. PFAS catalyzes the fourth step of IMP biosynthesis. Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis.
Alternative Symbols: FGAMS, FGARAT, KIAA0361, PURL
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Molecular Weight
- 147kDa
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Gene ID
- 5198
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NCBI Accession
- NP_036525
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UniProt
- O15067
Target
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