Poly (ADP-Ribose) Polymerase 2 (PARP2) (Middle Region) Peptide
Quick Overview for Poly (ADP-Ribose) Polymerase 2 (PARP2) (Middle Region) Peptide (ABIN8108430)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- PARP2 Peptide - middle region
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Sequence
- QRNFSVWMRW GRVGKTGQHS LVTCSGDLNK AKEIFQKKFL DKTKNNWEDR
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Poly (ADP-Ribose) Polymerase 2 (PARP2) peptide
PARP2 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- PARP2 Antibody (ARP89820_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
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Background
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Background Information: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates serine ADP-ribosylation of target proteins following interaction with HPF1, HPF1 conferring serine specificity (By similarity).
Alternative Symbols: ARTD2, Adprt2, C78626, PARP-2, Adprtl2, Aspartl2
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Molecular Weight
- 61 kDa
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Gene ID
- 11546
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NCBI Accession
- NP_033762
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UniProt
- O88554
Target
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