Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B) Peptide
Quick Overview for Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B) Peptide (ABIN8108543)
Target
Source
Application
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Purpose
- POLR2B Peptide
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-POLR2B antibody ( ARP32457_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
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Background
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Targeted Subunit: RPB2
Background Information: POLR2B is the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.
Alternative Symbols: RPB2, POL2RB, hsRPB2, hRPB140
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Molecular Weight
- 134kDa
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Gene ID
- 5431
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NCBI Accession
- NP_000929
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UniProt
- P30876
Target
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