Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (Middle Region) Peptide
Quick Overview for Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (Middle Region) Peptide (ABIN8109024)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- PSTPIP1 Peptide - middle region
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Sequence
- GHQKQVEKSQ NKARQCKDSA TEAERVYRQS IAQLEKVRAE WEQEHRTTCE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- PSTPIP1 Antibody (ARP81434_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
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Background
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Background Information: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Alternative Symbols: H-PIP, PAPAS, CD2BP1, PSTPIP, CD2BP1L, CD2BP1S
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Molecular Weight
- 48 kDa
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Gene ID
- 9051
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NCBI Accession
- NP_003969
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UniProt
- O43586
Target
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