Retinoblastoma Binding Protein 4 (RBBP4) (C-Term) Peptide
Quick Overview for Retinoblastoma Binding Protein 4 (RBBP4) (C-Term) Peptide (ABIN8110376)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- Rbbp4 Peptide - C-terminal region
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Sequence
- TAKISDFSWN PNEPWVICSV SEDNIMQVWQ MAENIYNDED PEGSVDPEGQ
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-Rbbp4 Antibody (ARP56649_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Retinoblastoma Binding Protein 4 (RBBP4)
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Background
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Background Information: Rbbp4 is a core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.
Alternative Symbols: mRbAp48
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Molecular Weight
- 47kDa
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Gene ID
- 19646
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NCBI Accession
- NM_009030
Target
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