rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB) (N-Term) Peptide
Quick Overview for rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB) (N-Term) Peptide (ABIN8110476)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- ARHGDIB Peptide - N-terminal region
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Sequence
- MTEKAPEPHV EEDDDDELDS KLNYKPPPQK SLKELQEMDK DDESLIKYKK
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ARHGDIB Antibody (ARP61689_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
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Background
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Background Information: Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases.
Alternative Symbols: D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2
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Molecular Weight
- 23kDa
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Gene ID
- 397
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NCBI Accession
- NP_001166
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UniProt
- P52566
Target
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