Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC) (Middle Region) Peptide
Quick Overview for Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC) (Middle Region) Peptide (ABIN8111243)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- SPARC Peptide - middle region
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Sequence
- YIPPCLDSEL TEFPLRMRDW LKNVLVTLYE RDEDNNLLTE KQKLRVKKIH
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))
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Background
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Background Information: This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: ON, BM-40
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Molecular Weight
- 35 kDa
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Gene ID
- 6678
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NCBI Accession
- NP_003109
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UniProt
- P09486
Target
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