Sequestosome 1 (SQSTM1) (Middle Region) Peptide
Quick Overview for Sequestosome 1 (SQSTM1) (Middle Region) Peptide (ABIN8111330)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- SQSTM1 Peptide - middle region
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Sequence
- RKIALESEGR PEEQMESDNC SGGDDDWTHL SSKEVDPSTG ELQSLQMPES
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- SQSTM1 Antibody (ARP97313_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- SQSTM1 (Sequestosome 1 (SQSTM1))
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Background
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Background Information: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Alternative Symbols: p60, p62, A170, OSIL, PDB3, ZIP3, p62B, FTDALS3
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Molecular Weight
- 39 kDa
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Gene ID
- 8878
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NCBI Accession
- NP_001135770
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UniProt
- Q13501
Target
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