Sirtuin 1 (SIRT1) (Middle Region) Peptide
Quick Overview for Sirtuin 1 (SIRT1) (Middle Region) Peptide (ABIN8111798)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- SIRT1 Peptide - middle region
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Sequence
- VSEDSSSPER TSPPDSSVIV TLLDQAAKSN DDLDVSESKG CMEEKPQEVQ
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Sirtuin 1 (SIRT1) peptide
SIRT1 Reactivity: Human, Mouse, Rat, Dog Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- SIRT1 Antibody (ARP97279_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- SIRT1 (Sirtuin 1 (SIRT1))
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Background
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Background Information: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
Alternative Symbols: SIR2, SIR2L1, SIR2alpha
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Molecular Weight
- 82 kDa
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Gene ID
- 23411
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NCBI Accession
- NP_001135970
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UniProt
- Q96EB6
Target
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