Src Homology 2 Domain Containing Adaptor Protein B (SHB) (N-Term) Peptide
Quick Overview for Src Homology 2 Domain Containing Adaptor Protein B (SHB) (N-Term) Peptide (ABIN8112775)
Target
Source
Application
-
-
Protein Region
- N-Term
-
Purpose
- SHB Peptide - N-terminal region
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-SHB antibody ( ARP58763_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
-
Background
-
Background Information: SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Alternative Symbols: RP11-3J10.8, bA3J10.2
-
Molecular Weight
- 55kDa
-
Gene ID
- 6461
-
NCBI Accession
- NP_003019
-
UniProt
- Q15464
Target
-
