Thyroid Hormone Receptor Interactor 4 (TRIP4) (Middle Region) Peptide
Quick Overview for Thyroid Hormone Receptor Interactor 4 (TRIP4) (Middle Region) Peptide (ABIN8113872)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- TRIP4 Peptide - middle region
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Sequence
- FKKDEILDGQ KSGDHLKRGR KKGRNRQEVP AFTEPDTTAE VKTPFDLAKA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- TRIP4 Antibody (ARP85792_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))
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Background
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Background Information: This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).
Alternative Symbols: ASC1, ASC-1, ZC2HC5, HsT17391
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Molecular Weight
- 63 kDa
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Gene ID
- 9325
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NCBI Accession
- NP_057297
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UniProt
- Q15650
Target
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