Transmembrane Protease, serine 2 (TMPRSS2) (C-Term) Peptide
Quick Overview for Transmembrane Protease, serine 2 (TMPRSS2) (C-Term) Peptide (ABIN8114413)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- TMPRSS2 Peptide - C-terminal region
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Sequence
- GAGYQVEKVI SHPNYDSKTK NNDIALMKLQ KPLTFNDLVK PVCLPNPGMM
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-TMPS2 Antibody (ARP46628_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))
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Background
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Background Information: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: PP9284, PRSS10
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Molecular Weight
- 54kDa
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Gene ID
- 7113
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NCBI Accession
- NP_005647
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UniProt
- O15393
Target
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