Transmembrane Protease, Serine 3 (TMPRSS3) (N-Term) Peptide
Quick Overview for Transmembrane Protease, Serine 3 (TMPRSS3) (N-Term) Peptide (ABIN8114417)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- TMPRSS3 Peptide - N-terminal region
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Sequence
- MGENDPPAVE APFSFRSLFG LDDLKISPVA PDADAVAAQI LSLLPLKFFP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-TMPRSS3 Antibody(ARP57684_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))
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Background
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Background Information: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
Alternative Symbols: DFNB10, DFNB8, ECHOS1, TADG12
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Molecular Weight
- 37kDa
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Gene ID
- 64699
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NCBI Accession
- NP_115781
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UniProt
- Q8WY52
Target
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