Ubiquitin Specific Peptidase 21 (USP21) (N-Term) Peptide
Quick Overview for Ubiquitin Specific Peptidase 21 (USP21) (N-Term) Peptide (ABIN8115204)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- Usp21 Peptide - N-terminal region
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Sequence
- PLPPRPGPPD ERLKKLELGR GRTSGSRPRG PLRADHGVPL PGSPPPAVAL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-Usp21 Antibody (ARP54439_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- USP21 (Ubiquitin Specific Peptidase 21 (USP21))
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Background
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Background Information: Usp21 deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Usp21 regulates gene expression via histone H2A deubiquitination. It is also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.
Alternative Symbols: ESTM28, Usp16, Usp23, W53272
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Molecular Weight
- 62kDa
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Gene ID
- 30941
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NCBI Accession
- NP_038947
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UniProt
- Q9QZL6
Target
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