Uracil-DNA Glycosylase (UNG) (N-Term) Peptide
Quick Overview for Uracil-DNA Glycosylase (UNG) (N-Term) Peptide (ABIN8115517)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- UNG Peptide - N-terminal region
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Sequence
- LYSFFSPSPA RKRHAPSPEP AVQGTGVAGV PEESGDAAAI PAKKAPAGQE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- UNG Antibody (ARP88038_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UNG (Uracil-DNA Glycosylase (UNG))
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Background
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Background Information: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Alternative Symbols: DGU, UDG, UNG1, UNG2, HIGM4, HIGM5, UNG15
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Molecular Weight
- 35 kDa
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Gene ID
- 7374
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NCBI Accession
- NP_003353
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UniProt
- P13051
Target
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