Vacuolar Protein Sorting 4 Homolog B (vps4b) (N-Term) Peptide
Quick Overview for Vacuolar Protein Sorting 4 Homolog B (vps4b) (N-Term) Peptide (ABIN8115625)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- VPS4B Peptide - N-terminal region
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Sequence
- EKLKEYLKNK EKKAQKPVKE GQPSPADEKG NDSDGEGESD DPEKKKLQNQ
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-VPS4B Antibody (ARP61680_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
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Background
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Background Information: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16.
Alternative Symbols: MIG1, SKD1, SKD1B, VPS4-2
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Molecular Weight
- 49kDa
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Gene ID
- 9525
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NCBI Accession
- NP_004860
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UniProt
- O75351
Target
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