Vesicle-Associated Membrane Protein 7 (VAMP7) (C-Term) Peptide
Quick Overview for Vesicle-Associated Membrane Protein 7 (VAMP7) (C-Term) Peptide (ABIN8115713)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- Vamp7 Peptide - C-terminal region
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Sequence
- DELKGIMVRN IDLVAQRGER LELLIDKTEN LVDSSVTFKT TSRNLARAMC
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-Vamp7 Antibody (ARP47593_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))
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Background
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Background Information: Vamp7 is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Vamp7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion.Vamp7 is required for calcium regulated lysosomal exocytosis. Vamp7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi.Vamp7 is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Vamp7 is also required for focal exocytosis of late endocytic vesicles during phagosome formation.
Alternative Symbols: Sybl1, TI-VAMP, VAMP-7
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Molecular Weight
- 25kDa
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Gene ID
- 20955
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NCBI Accession
- NP_035645
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UniProt
- P70280
Target
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