Interleukin 1, beta (IL1B) (AA 117-269) Peptide
Quick Overview for Interleukin 1, beta (IL1B) (AA 117-269) Peptide (ABIN934955)
Target
Origin
Source
Application
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Peptide Type
- Recombinant
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Protein Region
- AA 117-269
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Sequence
- MAPVRSLNCT LRDSQQKSLV MSGPYELKAL HLQGQDMEQQ VVFSMSFVQG EESNDKIPVA LGLKEKNLYL SCVLKDDKPT LQLESVDPKN YPKKKMEKRF VFNKIEINNK LEFESAQFPN WYISTSQAEN MPVFLGGTKG GQDITDFTMQ FVSS
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Characteristics
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Purified recombinant Human IL1 beta protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. -
Purity
- > 95 % pure
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Endotoxin Level
- < 1.0 EU per µg of protein (determined by LAL method)
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Application Notes
- IL1 beta protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in PBS, pH 7.4.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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: "Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers." in: Biomaterials, Vol. 31, Issue 6, pp. 1392-402, (2010) (PubMed).
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: "Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers." in: Biomaterials, Vol. 31, Issue 6, pp. 1392-402, (2010) (PubMed).
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Background
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Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1 alpha and IL-1 beta. IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta bind to the same receptor and they are structurally related polypeptides that share approximately 20 % amino acid. Recombinant human IL-1 beta was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: IL beta 1 protein, IL1-beta protein, IL1B protein, Interleukin 1b protein, IL beta 1, IL-1B, Interleukin 1beta protein, IL1F2 protein, beta proprotein protein, IL-1 protein, IL beta-1, IL1 beta, interleukin 1 beta protein, Interleukin 1 protein, IL beta-1 protein -
Molecular Weight
- 17 kDa (154 AA)
Target
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