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Interleukin 1, beta (IL1B) (AA 117-269) Peptide

IL1B Reactivity: Human Host: Escherichia coli (E. coli) SDS
Catalog No. ABIN934955

Quick Overview for Interleukin 1, beta (IL1B) (AA 117-269) Peptide (ABIN934955)

Target

IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Origin

Human

Source

  • 12
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)
  • Peptide Type

    Recombinant

    Protein Region

    AA 117-269

    Sequence

    MAPVRSLNCT LRDSQQKSLV MSGPYELKAL HLQGQDMEQQ VVFSMSFVQG EESNDKIPVA LGLKEKNLYL SCVLKDDKPT LQLESVDPKN YPKKKMEKRF VFNKIEINNK LEFESAQFPN WYISTSQAEN MPVFLGGTKG GQDITDFTMQ FVSS

    Characteristics

    Purified recombinant Human IL1 beta protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.

    Purity

    > 95 % pure

    Endotoxin Level

    < 1.0 EU per µg of protein (determined by LAL method)
  • Application Notes

    IL1 beta protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Supplied as a liquid in PBS, pH 7.4.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C

    Storage Comment

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Charoenphol, Huang, Eniola-Adefeso: "Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers." in: Biomaterials, Vol. 31, Issue 6, pp. 1392-402, (2010) (PubMed).

  • Target

    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

    Background

    Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1 alpha and IL-1 beta. IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta bind to the same receptor and they are structurally related polypeptides that share approximately 20 % amino acid. Recombinant human IL-1 beta was expressed in E. coli and purified by using conventional chromatography techniques.
    Alternative Names: IL beta 1 protein, IL1-beta protein, IL1B protein, Interleukin 1b protein, IL beta 1, IL-1B, Interleukin 1beta protein, IL1F2 protein, beta proprotein protein, IL-1 protein, IL beta-1, IL1 beta, interleukin 1 beta protein, Interleukin 1 protein, IL beta-1 protein

    Molecular Weight

    17 kDa (154 AA)
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