Interleukin 1, beta (IL1B) (N-Term) Peptide
-
- Target See all IL-1 beta (IL1B) products
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- MAEVPELASE MMAYYSGNED DLFFEADGPK QMKCSFQDLD LCPLDGGIQL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-IL1B Antibody(ARP54323_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
Interleukin 1, beta (IL1B) (AA 117-269) peptide
IL1B Reactivity: Human Host: Escherichia coli (E. coli) SDS
Interleukin 1, beta (IL1B) (AA 199-214) peptide (Ovalbumin)IL1B Reactivity: Rat Host: Synthetic WB, SDS, Imm
Interleukin 1, beta (IL1B) (AA 199-214) peptide (Ovalbumin)IL1B Reactivity: Mouse Host: Synthetic WB, SDS, Imm
Interleukin 1, beta (IL1B) (AA 199-214) peptide (BSA)IL1B Reactivity: Rat Host: Synthetic WB, SDS, Imm
Interleukin 1, beta (IL1B) (AA 199-214) peptide (BSA)IL1B Reactivity: Mouse Host: Synthetic WB, SDS, Imm
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Synonyms
- IL-1 Peptide, IL1-BETA Peptide, IL1F2 Peptide, IL-1BETA Peptide, IL1beta Peptide, il1-b Peptide, zgc:111873 Peptide, IL-1B Peptide, IL-1beta Peptide, Il-1b Peptide, IL1B Peptide, IL-1 beta Peptide, IL-1b Peptide, interleukin 1 beta Peptide, interleukin 1, beta Peptide, IL1B Peptide, il1b Peptide, Il1b Peptide
- Background
-
IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Alias Symbols: IL-1, IL1-BETA, IL1F2
Protein Interaction Partner: A2M,ADRB2,CASP1,CASP4,IL1B,IL1R1,IL1R2,IL1RAP,MMP2,PRTN3,IL1R1,MAPK8IP2,UBE2N,ZNF675
Protein Size: 269 - Molecular Weight
- 17 kDa
- Gene ID
- 3553
- NCBI Accession
- NM_000576, NP_000567
- UniProt
- P01584
-
