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- Target See all IgG2b products
- IgG2b
- Peptide Type
- Recombinant
- Protein Region
- AA 502-683
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MGTVMDVLKG DNRFSMLVAA IQSAGLTETL NREGVYTVFA PTNEAFRALP PRERSRLLGD AKELANILKY HIGDEILVSG GIGALVRLKS LQGDKLEVSL KNNVVSVNKE PVAEPDIMAT NGVVHVITNV LQPPANRPQE RGDELADSAL EIFKQASAFS RASQRSVRLA PVYQKLLERM KH
- Characteristics
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Purified recombinant Human BIGH3 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - Purity
- > 95 % pure
- Endotoxin Level
- < 1.0 EU per µg of protein (determined by LAL method)
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IgG2b peptide (Ovalbumin)
Reactivity: Mouse Host: Synthetic SDS, Imm, WB
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- Application Notes
- BIGH3 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied as a liquid in 20 mM Tris-HCl, pH 8.0, containing 0 mM EDTA, 0.0 mM PMSF, and 20 % glycerol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- IgG2b
- Synonyms
- IgG2b Peptide, Igh-3 Peptide, gamma2b Peptide, immunoglobulin heavy constant gamma 2B Peptide, Ighg2b Peptide
- Target Type
- Antibody
- Background
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BIGH3, also known as TGFBI and Beta ig-h3, is an extracellular matrix protein induced by transforming growth factor(TGF)-beta 1. BIGH3 protein is involved in cell growth, cell differentiation, wound healing and cell adhesion. In addition, some missense mutations of BIGH3 were identified in families affected with human autosomal dominant corneal dystrophies. BIGH3 gene encodes for a 683 amino-acid protein containing an RGD motif and four internal repeated domains which have highly conserved sequences founded in several species (Fasciclin domain). Recombinant human BIGH3 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: BIGH-3 protein, CDGG1 protein, CDG2 protein, BIGH 3, RGD CAP protein, MGC150270 protein, AI747162 protein, RGD-CAP protein, TGFBI transforming growth factor protein, TGFBI protein, CSD2 protein, LCD1 protein, EBMD protein, CSD protein, Beta ig h3 protein, CDB1 protein, BIGH3 protein, BIGH 3 protein, CSD1 protein, AI181842 protein, Kerato epithelin protein, Beta ig protein, CSD3 protein, BIGH3, BIGH-3, Big h3 protein, Beta ig-h3 protein, beta induced protein, 68kDa protein, Transforming growth factor-beta-induced protein ig-h3 RGD containing collagen associated protein protein, Transforming growth factor beta induced protein ig h3., Kerato-epithelin protein - Molecular Weight
- 19.9 kDa (182 AA)
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