Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Peptide
LDLRAP1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all LDLRAP1 products
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- WTDTRETLLE GMLFSLKYLG MTLVEQPKGE ELSAAAIKRI VATAKASGKK
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of LDLRAP1 antibody,
Alternative Names: LDLRAP1 control peptide, LDLRAP1 antibody Blocking Peptide, Anti-LDLRAP1 Blocking Peptide, Low Density Lipoprotein Receptor Adaptor Protein 1 Blocking Peptide, ARH Blocking Peptide, ARH1 Blocking Peptide, ARH2 Blocking Peptide, DKFZp586D0624 Blocking Peptide, FHCB1 Blocking Peptide, FHCB2 Blocking Peptide, MGC34705 Blocking Peptide, LDLRAP1, LDLRAP-1, LDLRAP 1, LDLRAP-1 Blocking Peptide, LDLRAP 1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
- Synonyms
- ARH Peptide, ARH1 Peptide, ARH2 Peptide, FHCB1 Peptide, FHCB2 Peptide, AA691260 Peptide, Arh Peptide, Arh1 Peptide, RGD1563417 Peptide, arh Peptide, arh1 Peptide, arh2 Peptide, fhcb1 Peptide, fhcb2 Peptide, xptb Peptide, LDLRAP1 Peptide, ldlrap1 Peptide, sb:cb50 Peptide, zgc:56121 Peptide, zgc:158745 Peptide, low density lipoprotein receptor adaptor protein 1 Peptide, low density lipoprotein receptor adaptor protein 1 L homeolog Peptide, low density lipoprotein receptor adaptor protein 1 S homeolog Peptide, low density lipoprotein receptor adaptor protein 1a Peptide, low density lipoprotein receptor adaptor protein 1b Peptide, LDLRAP1 Peptide, Ldlrap1 Peptide, ldlrap1 Peptide, ldlrap1.L Peptide, ldlrap1.S Peptide, ldlrap1a Peptide, ldlrap1b Peptide
- Background
- LDLRAP1 is an adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. LDLRAP1 may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits.
- Molecular Weight
- 34 kDa
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