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Isoleucyl-tRNA Synthetase (IARS) Peptide

IARS Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN936037
  • Target See all IARS products
    IARS (Isoleucyl-tRNA Synthetase (IARS))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    YEAAKVFGLR SRKLKLFLNE TQTQEITEDI PVKTLNMKTV YVSVLPTTAD
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of IARS antibody,
    Alternative Names: IARS control peptide, IARS antibody Blocking Peptide, Anti-IARS Blocking Peptide, Isoleucyl-tRNA Synthetase Blocking Peptide, FLJ20736 Blocking Peptide, IARS1 Blocking Peptide, ILRS Blocking Peptide, PRO0785 Blocking Peptide
    Purification
    Affinity chromatography using phosphopeptide and cross-adsorbed with the corresponding non-phosphopeptide.
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    IARS (Isoleucyl-tRNA Synthetase (IARS))
    Synonyms
    fi46h05 Peptide, zgc:63790 Peptide, wu:fi46h05 Peptide, K19E20.18 Peptide, K19E20_18 Peptide, ovule abortion 2 Peptide, ECK0027 Peptide, ilvS Peptide, JW0024 Peptide, An08g06770 Peptide, AO090012000505 Peptide, 2510016L12Rik Peptide, AI327140 Peptide, AU044614 Peptide, E430001P04Rik Peptide, ILRS Peptide, Iarsl Peptide, IARS1 Peptide, ILERS Peptide, IRS Peptide, PRO0785 Peptide, isoleucyl-tRNA synthetase Peptide, tRNA synthetase class I (I, L, M and V) family protein Peptide, isoleucine--tRNA ligase Peptide, isoleucyl-tRNA synthetase, cytoplasmic Peptide, isoleucine-tRNA synthetase Peptide, iars Peptide, IARS Peptide, OVA2 Peptide, ileS Peptide, MBAR_RS19160 Peptide, Rmag_0340 Peptide, ANI_1_964074 Peptide, CHLREDRAFT_106327 Peptide, EDI_049880 Peptide, OE_RS08520 Peptide, AOR_1_1912194 Peptide, Iars Peptide
    Background
    Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
    Molecular Weight
    144 kDa
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