Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptide
SDHB
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936209
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptide (ABIN936209)
Target
SDHB
(Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- YRWMIDSRDD FTEERLAKLQ DPFSLYRCHT IMNCTRTCPK GLNPGKAIAE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SDHB antibody,
Alternative Names: SDHB control peptide, SDHB antibody Blocking Peptide, Anti-SDHB Blocking Peptide, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Blocking Peptide, IP Blocking Peptide, PGL4 Blocking Peptide, SDH Blocking Peptide, SDH1 Blocking Peptide, SDHIP Blocking Peptide
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Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) peptide
SDHB Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
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Background
- Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
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Molecular Weight
- 31 kDa
Target
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