TNF Receptor-Associated Factor 6 (TRAF6) Peptide
TRAF6
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all TRAF6 products
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- YVTFMHLEAL RQRTFIKDDT LLVRCEVSTR FDMGSLRREG FQPRSTDAGV
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TRAF6 antibody,
Alternative Names: TRAF6 control peptide, TRAF6 antibody Blocking Peptide, Anti-TRAF6 Blocking Peptide, TNF receptor-associated factor 6 Blocking Peptide, MGC:3310 Blocking Peptide, RNF85 Blocking Peptide, TRAF6, TRAF-6, TRAF 6, TRAF-6 Blocking Peptide, TRAF 6 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
- Synonyms
- MGC:3310 Peptide, RNF85 Peptide, 2310003F17Rik Peptide, AI851288 Peptide, C630032O20Rik Peptide, rnf85 Peptide, traf6 Peptide, xtraf6 Peptide, CG10961 Peptide, DTRAF2 Peptide, Dmel\\CG10961 Peptide, TRAF Peptide, TRAF2 Peptide, TRAF6 Peptide, Traf2 Peptide, dTRAF2 Peptide, dTRAF6 Peptide, dTraf2 Peptide, dtraf2 Peptide, GB10539 Peptide, fi15f02 Peptide, wu:fi15f02 Peptide, zgc:63704 Peptide, TNF receptor associated factor 6 Peptide, TNF receptor-associated factor 6 Peptide, TNF receptor associated factor 6 L homeolog Peptide, TNF-receptor-associated factor 6 Peptide, TNF receptor associated factor 6 S homeolog Peptide, TRAF6 Peptide, Traf6 Peptide, traf6.L Peptide, traf6 Peptide, LOC551819 Peptide, traf6.S Peptide
- Background
- TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein.
- Molecular Weight
- 59 kDa
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