Galanin Receptor 2 (GALR2) Peptide
GALR2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all GALR2 products
- GALR2 (Galanin Receptor 2 (GALR2))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- RGTHSGSVLE RESSDLLHMS EAAGALRPCP GASQPCILEP CPGPSWQGPK
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GALR2 antibody,
Alternative Names: GALR2 control peptide, GALR2 antibody Blocking Peptide, Anti-GALR2 Blocking Peptide, galanin receptor 2 Blocking Peptide, GALNR2 Blocking Peptide, MGC125983 Blocking Peptide, MGC125984 Blocking Peptide, GALR2, GALR-2, GALR 2, GALR-2 Blocking Peptide, GALR 2 Blocking Peptide
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Galanin Receptor 2 (GALR2) peptide
GALR2 Reactivity: Human, Cow, Mouse, Dog, Rat Host: Synthetic BP, Imm
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- GALR2 (Galanin Receptor 2 (GALR2))
- Synonyms
- GALNR2 Peptide, mGalR Peptide, GALR2 Peptide, GAL2-R Peptide, GALR-2 Peptide, galanin receptor 2 Peptide, transcription regulator. LacI family, raffinose related Peptide, DNA-binding transcriptional regulator GalR Peptide, galactose operon repressor Peptide, galanin receptor type 2 Peptide, GALR2 Peptide, Galr2 Peptide, LOC100037698 Peptide, rafR Peptide, galR2 Peptide, LOC103690156 Peptide
- Background
- Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
- Molecular Weight
- 43 kDa
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