Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) Peptide
Quick Overview for Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) Peptide (ABIN936523)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- AELGAKAKEF TNVYIKNFGE EVDDESLKEL FSQFGKTLSV KVMRDPNGKS
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PABPC4 antibody,
Alternative Names: PABPC4 control peptide, PABPC4 antibody Blocking Peptide, Anti-PABPC4 Blocking Peptide, Poly A binding protein 4 Blocking Peptide, PABPC4, PABPC-4, PABPC 4, PABPC-4 Blocking Peptide, PABPC 4 Blocking Peptide -
Purification
- Purified
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
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Background
- Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells.
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Molecular Weight
- 71 kDa
Target
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