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Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) Peptide

PABPC4 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN936523

Quick Overview for Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) Peptide (ABIN936523)

Target

PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

Origin

Mammalian

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    AELGAKAKEF TNVYIKNFGE EVDDESLKEL FSQFGKTLSV KVMRDPNGKS

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of PABPC4 antibody,
    Alternative Names: PABPC4 control peptide, PABPC4 antibody Blocking Peptide, Anti-PABPC4 Blocking Peptide, Poly A binding protein 4 Blocking Peptide, PABPC4, PABPC-4, PABPC 4, PABPC-4 Blocking Peptide, PABPC 4 Blocking Peptide

    Purification

    Purified
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

    Background

    Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells.

    Molecular Weight

    71 kDa
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