FACT complex subunit SPT16 (SUPT16H) Peptide
SUPT16H
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936897
Quick Overview for FACT complex subunit SPT16 (SUPT16H) Peptide (ABIN936897)
Target
SUPT16H
(FACT complex subunit SPT16 (SUPT16H))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ASKKKVEFLK QIANTKGNEN ANGAPAITLL IREKNESNKS SFDKMIEAIK
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SUPT16 H antibody,
Alternative Names: SUPT16H control peptide, SUPT16H antibody Blocking Peptide, Anti-SUPT16H Blocking Peptide, suppressor of Ty 16 homolog, S. cerevisiae Blocking Peptide, CDC68 Blocking Peptide, FACT Blocking Peptide, FACTP140 Blocking Peptide, FLJ10857 Blocking Peptide, FLJ14010 Blocking Peptide, FLJ34357 Blocking Peptide, SPT16/CDC68 Blocking Peptide, SUPT16H, SUPTH-16, SUPTH 16, SUPTH-16 Blocking Peptide, SUPTH 16 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
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Background
- Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H.
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Molecular Weight
- 66 kDa
Target
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