FACT complex subunit SPT16 (SUPT16H) (Middle Region) Peptide
SUPT16H
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SUPT16H products
- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SUPT16H antibody (Catalog #: ARP38921_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
- Synonyms
- CDC68 Peptide, FACTP140 Peptide, SPT16/CDC68 Peptide, CG1828 Peptide, DRE4/dSPT16 Peptide, Dmel\\CG1828 Peptide, SPT16 Peptide, Spt16 Peptide, dSPT16 Peptide, dSpt16 Peptide, dspt16 Peptide, l(3)62Bg Peptide, l(3)dre4 Peptide, spt16 Peptide, Cdc68 Peptide, Fact140 Peptide, Supt16h Peptide, T12H20.3 Peptide, T12H20_3 Peptide, global transcription factor C Peptide, SSF1 Peptide, DDBDRAFT_0204912 Peptide, DDBDRAFT_0231753 Peptide, DDB_0204912 Peptide, DDB_0231753 Peptide, DUF140 Peptide, SPT16 homolog, facilitates chromatin remodeling subunit Peptide, FACT complex subunit spt16 Peptide, FACT complex subunit SPT16 Peptide, CG1828 gene product from transcript CG1828-RB Peptide, suppressor of Ty 16 Peptide, global transcription factor C Peptide, chromatin-remodeling protein SPT16 Peptide, FACT complex component Spt16 Peptide, chromatin-remodeling protein Peptide, global regulator of transcription Peptide, FACT (FAcilitates Chromatin Transcription) complex subunit, putative Peptide, SPT16 homolog, facilitates chromatin remodeling subunit S homeolog Peptide, SUPT16H Peptide, AOR_1_1808194 Peptide, CC1G_05155 Peptide, dre4 Peptide, Supt16 Peptide, SPT16 Peptide, spt16 Peptide, CDC68 Peptide, Supt16h Peptide, supt16h Peptide, supt16h.S Peptide
- Background
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Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H. Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is the protein encoded by this gene. Sequence Note: The sequence AF152961.1 is a chimeric mRNA clone. Only the SUPT16H region was propagated into this RefSeq record. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CDC68, FACT, FACTP140, FLJ10857, FLJ14010, FLJ34357, SPT16/CDC68
Protein Interaction Partner: H3F3A,HES1,GTF2E2,H3F3B,MCM3,MCM4,NEK9,SFRS12,BAZ1B,BRCC3,HIST2H2BE
Protein Size: 1047 - Molecular Weight
- 120 kDa
- Gene ID
- 11198
- NCBI Accession
- NM_007192, NP_009123
- UniProt
- Q9Y5B9
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