Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) Peptide
CYP1B1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936970
Quick Overview for Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) Peptide (ABIN936970)
Target
CYP1B1
(Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- AVANVMSAVC FGCRYSHDDP EFRELLSHNE EFGRTVGAGS LVDVMPWLQY
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CYP1 B1 antibody,
Alternative Names: CYP1B1 control peptide, CYP1B1 antibody Blocking Peptide, Anti-CYP1B1 Blocking Peptide, Cytochrome P450 Family 1 Subfamily B Polypeptide 1 Blocking Peptide, CP1B Blocking Peptide, GLC3A Blocking Peptide, CYP1B1, CYPB-1, CYPB 1, CYPB-1 Blocking Peptide, CYPB 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
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Background
- CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1B1 localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
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Molecular Weight
- 61 kDa
Target
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