Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) Peptide
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- Target See all CYP1B1 products
- CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CYP1B1 antibody (Catalog #: ARP51761_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
- Synonyms
- CP1B Peptide, CYPIB1 Peptide, GLC3A Peptide, P4501B1 Peptide, P4501b1 Peptide, CYP1B1 Peptide, CYP1B Peptide, zgc:136223 Peptide, cytochrome P450 family 1 subfamily B member 1 Peptide, cytochrome P450, family 1, subfamily b, polypeptide 1 Peptide, cytochrome P450, family 1, subfamily B, polypeptide 1 Peptide, cytochrome P450 1B1 Peptide, CYP1B1 Peptide, Cyp1b1 Peptide, cyp1b1 Peptide, LOC100719054 Peptide
- Background
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CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1B1 localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CP1B, GLC3A, P4501B1, CYPIB1
Protein Interaction Partner: SAE1
Protein Size: 543 - Molecular Weight
- 61 kDa
- Gene ID
- 1545
- NCBI Accession
- NM_000104, NP_000095
- UniProt
- Q16678
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