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Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1) Peptide

CYP1B1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975517
  • Target See all CYP1B1 products
    CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CYP1B1 antibody (Catalog #: ARP51761_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
    Synonyms
    CP1B Peptide, CYPIB1 Peptide, GLC3A Peptide, P4501B1 Peptide, P4501b1 Peptide, CYP1B1 Peptide, CYP1B Peptide, zgc:136223 Peptide, cytochrome P450 family 1 subfamily B member 1 Peptide, cytochrome P450, family 1, subfamily b, polypeptide 1 Peptide, cytochrome P450, family 1, subfamily B, polypeptide 1 Peptide, cytochrome P450 1B1 Peptide, CYP1B1 Peptide, Cyp1b1 Peptide, cyp1b1 Peptide, LOC100719054 Peptide
    Background
    CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1B1 localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CP1B, GLC3A, P4501B1, CYPIB1

    Protein Interaction Partner: SAE1

    Protein Size: 543
    Molecular Weight
    61 kDa
    Gene ID
    1545
    NCBI Accession
    NM_000104, NP_000095
    UniProt
    Q16678
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