Poly(rC) Binding Protein 1 (PCBP1) Peptide
PCBP1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937190
Quick Overview for Poly(rC) Binding Protein 1 (PCBP1) Peptide (ABIN937190)
Target
PCBP1
(Poly(rC) Binding Protein 1 (PCBP1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- CSDAVGYPHA THDLEGPPLD AYSIQGQHTI SPLDLAKLNQ VARQQSHFAM
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PCBP1 antibody,
Alternative Names: PCBP1 control peptide, PCBP1 antibody Blocking Peptide, Anti-PCBP1 Blocking Peptide, Poly rC binding protein 1 Blocking Peptide, PCBP1, PCBP-1, PCBP 1, PCBP-1 Blocking Peptide, PCBP 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
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Background
- PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA.
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Molecular Weight
- 39 kDa
Target
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