Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1) Peptide
KATNA1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937273
Quick Overview for Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1) Peptide (ABIN937273)
Target
KATNA1
(Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Katna1 antibody,
Alternative Names: Katna1 control peptide, Katna1 antibody Blocking Peptide, Anti-Katna1 Blocking Peptide, katanin p60, ATPase-containing subunit A1 Blocking Peptide, Katna1, Katna-1, Katna 1, Katna-1 Blocking Peptide, Katna 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))
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Background
- Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins.
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Molecular Weight
- 54 kDa
Target
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