Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1) (C-Term) Peptide
KATNA1
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all KATNA1 products
- KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))
- Protein Region
- C-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DDPSKMVMVL AATNFPWDID EALRRRLEKR IYIPLPSAKG REELLRISLR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Katna1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KATNA1 (Katanin P60 (ATPase Containing) Subunit A 1 (KATNA1))
- Synonyms
- si:dkey-15j16.1 Peptide, zgc:110580 Peptide, katna1 Peptide, katanin catalytic subunit A1 Peptide, katanin p60 (ATPase containing) subunit A 1 Peptide, katanin p60 (ATPase-containing) subunit A1 Peptide, KATNA1 Peptide, katna1 Peptide, Katna1 Peptide
- Background
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Katna1 severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition.It may also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth.
Alias Symbols: -
Protein Size: 491 - Molecular Weight
- 54 kDa
- Gene ID
- 23924
- NCBI Accession
- NM_011835, NP_035965
- UniProt
- Q9WV86
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