Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1) Peptide
TNKS1BP1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937331
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1) Peptide (ABIN937331)
Target
TNKS1BP1
(Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DGEASQTEDV DGTWGSSAAR WSDQGPAQTS RRPSQGPPAR SPSQDFSFIE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TNKS1 BP1 antibody,
Alternative Names: TNKS1BP1 control peptide, TNKS1BP1 antibody Blocking Peptide, Anti-TNKS1BP1 Blocking Peptide, Tankyrase 1 Binding Protein 1 182Kda Blocking Peptide, FLJ45975 Blocking Peptide, KIAA1741 Blocking Peptide, TAB182 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
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Background
- TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
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Molecular Weight
- 190 kDa
Target
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