Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1) (Middle Region) Peptide
TNKS1BP1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985332
$160.46
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100 μg
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Quick Overview for Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1) (Middle Region) Peptide (ABIN985332)
Target
TNKS1BP1
(Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNKS1BP1 antibody (Catalog #: ARP58347_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TNKS1BP1 (Tankyrase 1 Binding Protein 1, 182kDa (TNKS1BP1))
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Background
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TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.
Alias Symbols: FLJ45975, KIAA1741, TAB182
Protein Interaction Partner: TNKS,TNKS2,TNKS,TNKS2
Protein Size: 1729 -
Molecular Weight
- 190 kDa
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Gene ID
- 85456
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NCBI Accession
- NM_033396, NP_203754
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UniProt
- Q9C0C2
Target
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