Interleukin 1, beta (IL1B) Peptide
Quick Overview for Interleukin 1, beta (IL1B) Peptide (ABIN937423)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- DLDLCPLDGG IQLRISDHHY SKGFRQAASV VVAMDKLRKM LVPCPQTFQE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of IL1 B antibody,
Alternative Names: IL1 beta control peptide, IL1 beta antibody Blocking Peptide, Anti-IL1 beta Blocking Peptide, Interleukin 1 Beta Blocking Peptide, IL-1 Blocking Peptide, IL1-BETA Blocking Peptide, IL1F2 Blocking Peptide, IL1B Blocking Peptide, IL1 beta, IL beta-1, IL beta 1, IL beta-1 Blocking Peptide, IL beta 1 Blocking Peptide
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Interleukin 1, beta (IL1B) (AA 117-269) peptide
IL1B Reactivity: Human Host: Escherichia coli (E. coli) SDS
Interleukin 1, beta (IL1B) (AA 199-214) peptide (BSA)IL1B Reactivity: Rat Host: Synthetic WB, SDS, Imm
Interleukin 1, beta (IL1B) (AA 199-214) peptide (BSA)IL1B Reactivity: Mouse Host: Synthetic WB, SDS, Imm
Interleukin 1, beta (IL1B) (AA 199-214) peptide (Ovalbumin)IL1B Reactivity: Rat Host: Synthetic WB, SDS, Imm
Interleukin 1, beta (IL1B) (AA 199-214) peptide (Ovalbumin)IL1B Reactivity: Mouse Host: Synthetic WB, SDS, Imm
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Background
- IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
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Molecular Weight
- 17 kDa
Target
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