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Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Peptide

KCNN3 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN937535
  • Target See all KCNN3 products
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    DRSEDLEKQI GSLESKLEHL TASFNSLPLL IADTLRQQQQ QLLSAIIEAR
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of KCNN3 antibody,
    Alternative Names: KCNN3 control peptide, KCNN3 antibody Blocking Peptide, Anti-KCNN3 Blocking Peptide, Potassium Intermediate/Small Conductance Calcium-Activated Channel Subfamily N Member 3 Blocking Peptide, KCNN3, KCNN-3, KCNN 3, KCNN-3 Blocking Peptide, KCNN 3 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    Synonyms
    KCa2.3 Peptide, SK3 Peptide, SKCA3 Peptide, hSK3 Peptide, potassium calcium-activated channel subfamily N member 3 Peptide, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 Peptide, Kcnn3 Peptide, KCNN3 Peptide
    Background
    Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by KCNN3 is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP.
    Molecular Weight
    47 kDa
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