Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) Peptide
Quick Overview for Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) Peptide (ABIN937620)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- DYAKKRGWVL GPNNYYSFAS QQQKPEDTTI PSTELAKQVI EYARQLEMIV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PSMD8 antibody,
Alternative Names: PSMD8 control peptide, PSMD8 antibody Blocking Peptide, Anti-PSMD8 Blocking Peptide, Proteasome macropain 26S subunit non-ATPase 8 Blocking Peptide, Prosome Macropain 26S Subunit Non-Atpase 8 Blocking Peptide, HIP6 Blocking Peptide, HYPF Blocking Peptide, MGC1660 Blocking Peptide, Nin1p Blocking Peptide, Rpn12 Blocking Peptide, S14 Blocking Peptide, p31 Blocking Peptide, PSMD8, PSMD-8, PSMD 8, PSMD-8 Blocking Peptide, PSMD 8 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
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Background
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. PSMD8 is a non-ATPase subunit of the 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
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Molecular Weight
- 27 kDa
Target
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