Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8) Peptide
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- Target See all PSMD8 products
- PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMD8 antibody (Catalog #: ARP48216_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
- Synonyms
- HIP6 Peptide, HYPF Peptide, Nin1p Peptide, Rpn12 Peptide, S14 Peptide, p31 Peptide, hip6 Peptide, hypf Peptide, nin1p Peptide, rpn12 Peptide, psmd8b Peptide, 6720456J22Rik Peptide, AA407360 Peptide, AL033291 Peptide, AL033322 Peptide, AL033323 Peptide, C76433 Peptide, psmd8 Peptide, psmd8a Peptide, fa93g07 Peptide, fb17c09 Peptide, fb49a10 Peptide, zgc:86762 Peptide, wu:fa93g07 Peptide, wu:fb17c09 Peptide, wu:fb49a10 Peptide, PSMD8 Peptide, proteasome 26S subunit, non-ATPase 8 Peptide, proteasome 26S subunit, non-ATPase 8 S homeolog Peptide, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Peptide, proteasome 26S subunit, non-ATPase 8 L homeolog Peptide, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 pseudogene Peptide, PSMD8 Peptide, psmd8.S Peptide, Psmd8 Peptide, psmd8.L Peptide, psmd8 Peptide, LOC468490 Peptide
- Background
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. PSMD8 is a non-ATPase subunit of the 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Alias Symbols: HIP6, HYPF, MGC1660, Nin1p, Rpn12, S14, p31
Protein Interaction Partner: UCHL5,SMAD2,SMAD9,UCHL5,PAAF1,PSMD13,PSMD6,UCHL5
Protein Size: 257 - Molecular Weight
- 27 kDa
- Gene ID
- 5714
- UniProt
- P48556
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