APOBEC1 Complementation Factor (A1CF) Peptide
A1CF
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937672
Quick Overview for APOBEC1 Complementation Factor (A1CF) Peptide (ABIN937672)
Target
A1CF
(APOBEC1 Complementation Factor (A1CF))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Peptide Type
- Synthetic
-
Sequence
- EAVCLGTCPE PEASMSTAIP GLKKGNNALQ SIILQTLLEK ENGQRKYGGP
-
Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of A1 CF antibody,
Alternative Names: A1CF control peptide, A1CF antibody Blocking Peptide, Anti-A1CF Blocking Peptide, Apobec1 Complementation Factor Blocking Peptide, ACF Blocking Peptide, ACF64 Blocking Peptide, ACF65 Blocking Peptide, APOBEC1CF Blocking Peptide, ASP Blocking Peptide, MGC163391 Blocking Peptide, RP.2 Blocking Peptide
-
-
-
-
Application Notes
- Optimal conditions should be determined by the investigator
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handling Advice
- Avoid repeated freeze/thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C long term.
-
-
- A1CF (APOBEC1 Complementation Factor (A1CF))
-
Background
- Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events.
-
Molecular Weight
- 65 kDa
Target
-
You are here:
