N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4) Peptide
Quick Overview for N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4) Peptide (ABIN937720)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- EDWTIFQYNH STYQPVLLTE LQTEKSLSSL SSKTLFATVI QDLGLHDGIQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of NDST4 antibody,
Alternative Names: NDST4 control peptide, NDST4 antibody Blocking Peptide, Anti-NDST4 Blocking Peptide, N-Deacetylase/N-Sulfotransferase Blocking Peptide, Heparan Glucosaminyl 4 Blocking Peptide, NDST4, NDST-4, NDST 4, NDST-4 Blocking Peptide, NDST 4 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- NDST4 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4))
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Background
- NDST4 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. It modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. NDST4 has low deacetylase activity but high sulfotransferase activity.
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Molecular Weight
- 101 kDa
Target
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