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N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4) Peptide

NDST4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN980559
  • Target See all NDST4 products
    NDST4 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4))
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-NDST4 antibody (Catalog #: ARP49737_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NDST4 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4))
    Synonyms
    NDST-4 Peptide, NHSST4 Peptide, 4930439H17Rik Peptide, N-deacetylase and N-sulfotransferase 4 Peptide, N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4 Peptide, NDST4 Peptide, Ndst4 Peptide
    Background
    NDST4 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. It modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. NDST4 has low deacetylase activity but high sulfotransferase activity.

    Alias Symbols: NDST-4, NHSST4

    Protein Size: 872
    Molecular Weight
    101 kDa
    Gene ID
    64579
    NCBI Accession
    NM_022569, NP_072091
    UniProt
    Q9H3R1
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