Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3) Peptide
UBA3
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
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- Target See all UBA3 products
- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Sequence
- EGRWNHVKKF LERSGPFTHP DFEPSTESLQ FLLDTCKVLV IGAGGLGCEL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of UBA3 antibody,
Alternative Names: UBA3 control peptide, UBA3 antibody Blocking Peptide, Anti-UBA3 Blocking Peptide, ubiquitin-like modifier activating enzyme 3 Blocking Peptide, DKFZp566J164 Blocking Peptide, MGC22384 Blocking Peptide, UBE1C Blocking Peptide, hUBA3 Blocking Peptide, UBA3, UBA-3, UBA 3, UBA-3 Blocking Peptide, UBA 3 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
- Synonyms
- UBE1C Peptide, hUBA3 Peptide, Ube1c Peptide, ube1c Peptide, wu:fb75e04 Peptide, wu:fc37b11 Peptide, zgc:55528 Peptide, A830034N06Rik Peptide, AI256736 Peptide, AI848246 Peptide, AW546539 Peptide, ubiquitin like modifier activating enzyme 3 Peptide, ubiquitin-like modifier activating enzyme 3 Peptide, ubiquitin like modifier activating enzyme 3 S homeolog Peptide, UBA3 Peptide, Uba3 Peptide, uba3 Peptide, uba3.S Peptide
- Background
- UBA3 is a catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. UBA3 down-regulates steroid receptor activity. UBA3 is necessary for cell cycle progression.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s.
- Molecular Weight
- 52 kDa
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