Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3) Peptide
UBA3
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN937832
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 16 to 22 Business Days
Quick Overview for Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3) Peptide (ABIN937832)
Target
UBA3
(Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Peptide Type
- Synthetic
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Sequence
- EGRWNHVKKF LERSGPFTHP DFEPSTESLQ FLLDTCKVLV IGAGGLGCEL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of UBA3 antibody,
Alternative Names: UBA3 control peptide, UBA3 antibody Blocking Peptide, Anti-UBA3 Blocking Peptide, ubiquitin-like modifier activating enzyme 3 Blocking Peptide, DKFZp566J164 Blocking Peptide, MGC22384 Blocking Peptide, UBE1C Blocking Peptide, hUBA3 Blocking Peptide, UBA3, UBA-3, UBA 3, UBA-3 Blocking Peptide, UBA 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
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Background
- UBA3 is a catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. UBA3 down-regulates steroid receptor activity. UBA3 is necessary for cell cycle progression.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s.
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Molecular Weight
- 52 kDa
Target
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