Splicing Factor 3b, Subunit 3, 130kDa (SF3B3) Peptide
SF3B3
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all SF3B3 products
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EHPPLCGRDH LSFRSYYFPV KNVIDGDLCE QFNSMEPNKQ KNVSEELDRT
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SF3 B3 antibody,
Alternative Names: SF3B3 control peptide, SF3B3 antibody Blocking Peptide, Anti-SF3B3 Blocking Peptide, Splicing Factor 3B Subunit 3 130Kda Blocking Peptide, KIAA0017 Blocking Peptide, RSE1 Blocking Peptide, SAP130 Blocking Peptide, SF3b130 Blocking Peptide, STAF130 Blocking Peptide, SF3B3, SFB-3, SFB 3, SFB-3 Blocking Peptide, SFB 3 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- Background
- SF3B3 is subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
- Molecular Weight
- 135 kDa
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