Interleukin 7 Receptor (IL7R) Peptide
IL7R
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all IL7R products
- IL7R (Interleukin 7 Receptor (IL7R))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of IL7 R antibody,
Alternative Names: IL7R control peptide, IL7R antibody Blocking Peptide, Anti-IL7R Blocking Peptide, interleukin 7 receptor Blocking Peptide, CD127 Blocking Peptide, CDW127 Blocking Peptide, IL-7R-alpha Blocking Peptide, IL7RA Blocking Peptide, ILRA Blocking Peptide, IL7R, ILR-7, ILR 7, ILR-7 Blocking Peptide, ILR 7 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- IL7R (Interleukin 7 Receptor (IL7R))
- Synonyms
- IL7R Peptide, CD127 Peptide, IL-7Ralpha Peptide, CDW127 Peptide, IL-7R-alpha Peptide, IL7RA Peptide, ILRA Peptide, IL-7RA Peptide, interleukin 7 receptor Peptide, IL7R Peptide, Il7r Peptide
- Background
- The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
- Molecular Weight
- 49 kDa
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