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Sepiapterin Reductase (SPR) Peptide

SPR Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938157
  • Target See all SPR products
    SPR (Sepiapterin Reductase (SPR))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of SPR antibody,
    Alternative Names: SPR control peptide, SPR antibody Blocking Peptide, Anti-SPR Blocking Peptide, sepiapterin reductase, 7,8-dihydrobiopterin:NADP+ oxidoreductase Blocking Peptide, SDR38C1 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    SPR (Sepiapterin Reductase (SPR))
    Synonyms
    SDR38C1 Peptide, AA409688 Peptide, ENSMUSG00000071345 Peptide, Gm10328 Peptide, CG12117 Peptide, Dmel\\CG12117 Peptide, SR Peptide, sptr Peptide, xspr Peptide, DDBDRAFT_0188686 Peptide, DDBDRAFT_0191275 Peptide, DDB_0188686 Peptide, DDB_0191275 Peptide, zgc:194446 Peptide, sepiapterin reductase Peptide, Sepiapterin reductase Peptide, sepiapterin reductase L homeolog Peptide, sepiapterin reductase b Peptide, SPR Peptide, Spr Peptide, Sptr Peptide, spr.L Peptide, sprE Peptide, CpipJ_CPIJ000511 Peptide, sr Peptide, spr Peptide, sprb Peptide
    Background
    This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
    Molecular Weight
    28 kDa
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