Hect Domain and RLD 5 (HERC5) Peptide
HERC5
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all HERC5 products
- HERC5 (Hect Domain and RLD 5 (HERC5))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- FHPEELKDVI VGNTDYDWKT FEKNARYEPG YNSSHPTIVM FWKAFHKLTL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of HERC5 antibody,
Alternative Names: HERC5 control peptide, HERC5 antibody Blocking Peptide, Anti-HERC5 Blocking Peptide, Hect Domain And Rld 5 Blocking Peptide, CEB1 Blocking Peptide, CEBP1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- HERC5 (Hect Domain and RLD 5 (HERC5))
- Synonyms
- HERC5 Peptide, CEB1 Peptide, CEBP1 Peptide, HECT and RLD domain containing E3 ubiquitin protein ligase 5 Peptide, hect domain and RLD 5 Peptide, HERC5 Peptide
- Background
- This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
- Molecular Weight
- 117 kDa
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