Histidyl-tRNA Synthetase (HARS1) Peptide
HARS1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938502
Quick Overview for Histidyl-tRNA Synthetase (HARS1) Peptide (ABIN938502)
Target
HARS1/Jo-1 (HARS1)
(Histidyl-tRNA Synthetase (HARS1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- FVLKTPKGTR DYSPRQMAVR EKVFDVIIRC FKRHGAEVID TPVFELKETL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of HARS antibody,
Alternative Names: HARS control peptide, HARS antibody Blocking Peptide, Anti-HARS Blocking Peptide, histidyl-tRNA synthetase Blocking Peptide, FLJ20491 Blocking Peptide, HRS Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
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Background
- Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
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Molecular Weight
- 56 kDa
Target
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