Histidyl-tRNA Synthetase (HARS1) (N-Term) Peptide
HARS1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HARS1/Jo-1 (HARS1) products
- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FVLKTPKGTR DYSPRQMAVR EKVFDVIIRC FKRHGAEVID TPVFELKETL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HARS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HARS1/Jo-1 (HARS1) (Histidyl-tRNA Synthetase (HARS1))
- Synonyms
- HRS Peptide, USH3B Peptide, MMHRS Peptide, Dnd1 Peptide, HARSL Peptide, histidyl-tRNA synthetase Peptide, HARS Peptide, Hars Peptide
- Background
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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Alias Symbols: FLJ20491, HRS, USH3B
Protein Interaction Partner: EEF1B2,EEF1G,EEF1B2,EEF1G,RPL5,TARS,EEF1B2,EEF1G
Protein Size: 509 - Molecular Weight
- 56 kDa
- Gene ID
- 3035
- NCBI Accession
- NM_002109, NP_002100
- UniProt
- P12081
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