Angiotensin I Converting Enzyme 2 (ACE2) Peptide
ACE2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938507
Quick Overview for Angiotensin I Converting Enzyme 2 (ACE2) Peptide (ABIN938507)
Target
ACE2
(Angiotensin I Converting Enzyme 2 (ACE2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- FVTAPKNVSD IIPRTEVEKA IRMSRSRIND AFRLNDNSLE FLGIQPTLGP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of ACE2 antibody,
Alternative Names: ACE2 control peptide, ACE2 antibody Blocking Peptide, Anti-ACE2 Blocking Peptide, Angiotensin I Converting Enzyme Blocking Peptide, Peptidyl-Dipeptidase A 2 Blocking Peptide, ACEH Blocking Peptide, DKFZP434A014 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
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Background
- ACE2 belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this geneuggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
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Molecular Weight
- 89 kDa
Target
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